Tissue Lysates
Cayman Chemical TIM4 EXrAClular DomaInh 100ug
Source: Recombinant human C-terminal His-tagged TIM-4 extracellular domain expressed in HEK293 cells • Amino acids: 25-315 • MW: 32.7 kDa
Cayman Chemical Thromboxn B3 100ug
A uremic toxin and metabolite of tryptophan activates AhR in HepG2 40/6 hepatoma cells (EC50 12 1 nM in a reporter assay) inhibits OAT1 and OAT3 (Kis 34 2 and 74 4 UM respectively for the rat transporters) in S2 proximal tubule cells increases superoxide anion and nitric oxide levels in isolated human mononuclear blood cells at 0 2 and 1 mM increases serum creatinine and BUN levels in the 5/6 nephrectomized rat model of chronic renal failure at 50 mg/kg
Abcam Rat liver tissue lysate - mitochondrial extract | 2mg
2 mg of purified rat liver mitochondrial membranes resuspended in 400 µl of heart mitochondria resuspension buffer (10 mM Tris.HCl, pH 7.8, 0.2 M sucrose, 0.2 mM EDTA, 1 mM PMSF). 1 mg solubilized mitochondria for Immunocapture experiments. For the Immunocapture of OXPHOS complexes it is recommended that 180 µl of the mitochondrial membranes supplied be solubilized by the addition of 20 µl of 10% lauryl maltoside. Insoluble material is removed by centrifugation at 72,000g before immunocapture of complexes from the supernatant.
Cayman Chemical 13HODE cholesTRyl esTR 100ug
(±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions{2227} and shown to be produced by Cu2+-catalyzed oxidation of LDL.{2228} Later studies determined that 15-LO from rabbit reticulocytes and human monocytes were able to metabolize cholesteryl linoleate, a major component of LDL, to 13-HODE cholesteryl ester.{1126,2412}
Sino Biological Recombinant Human CD9 Protein (Nanodisc, Full-length, His-GFP Tag), Fluorescent
A DNA sequence encoding the Human CD9 (P21926) (Met1-Val228) was expressed with a N-terminal polyhistidine tag followed by a GFP Tag. Nanodisc is a versatile tool for studying membrane proteins. Using styrene-maleic acid (SMA) copolymer, membrane proteins can be extracted directly from prokaryotic and eukaryotic expression systems in the absence of detergents to preserve the protein structure and function better. Compared to membrane scaffold proteins (MSPs) nanodiscs, SMA nanodiscs also have the advantage of preserving proteins' nature by maintaining native lipids surrounded without introducing any heterologous proteins, which allows studies of protein structure and functions in a native-like environment.
Cayman Chemical P-SelectInCD62Phumnreco 100ug
Source: Active recombinant C-terminal human IgG1 Fc-tagged P-selectin expressed in HEK293 cells • Amino acids: 42-771 • MW: 107 kDa
Cayman Chemical SynthetIc MIltIron 1mg
A tanshinone; protects lard from thermal oxidation at 0.02%; a partial agonist of the benzodiazepine receptor (IC50 = 0.3 µM); inhibits CES2 (Ki = 0.04 µM) as well as SARS-CoV Mpro and PLpro (IC50s = 21.1 and 30 µM, respectively); cytotoxic to HCT116 colon cancer cells (IC50 = 4.27 µM) and induces mitochondrial dysfunction and ROS production in the same cells; increases the number of punished crossings in the four-plate test, indicating tranquilizing activity, in mice at 10-60 mg/kg
Cayman Chemical SynthetIc GosypetIn 1mg
A flavonoid with diverse biological activities; inhibits MKK3 and MKK6, as well as induces apoptosis and cell cycle arrest at the G2 phase in KYSE-450 and KYSE-510 esophageal cancer cells at 20 µM; scavenges DPPH radicals and inhibits copper-induced lipid peroxidation in cell-free assays; reduces high-fat diet-induced increases in serum cholesterol, triglycerides, and LDL-cholesterol levels, as well as decreases aortic extracellular lipid and foam cell deposits in a rabbit model of atherosclerosis at 10 mg/kg
Cayman Chemical SynthetIc CBGM 1mg
An analytical reference standard categorized as a phytocannabinoid; intended for research and forensic applications
Cayman Chemical Cholesteryl-d7 PalmItate 1mg
An internal standard for the quantification of cholesteryl palmitate by GC- or LC-MS
Cayman Chemical 4-cyno CUMYL-BUTCZCA 1mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids; intended for research and forensic applications
Cayman Chemical SynthetIc PF-1022A 1mg
A cyclodepsipeptide with anthelmintic activity; oral administration induces worm excretion in a chicken model of A. galli infection from 0.5-2 mg/kg; induces parasite clearance in jird models of H. contortus, O. ostertagi, or T. colubriformis infection (ED95s = 0.11, 0.33, and 0.11 mg/animal)